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This dual effect accelerates HBV persistence and worsens liver disease progression

ISBN 978-0-7216-0240-0

By reducing excess fat, tirzepatide lowers the conversion of natural testosterone into estrogen and helps restore the bodys ability to maintain healthy testosterone levels

Trombelli L, Simonelli A, Pramstraller M, Wikesjo UM, Farina R

doi: 10.3389/fddev.2026.1692219 Received 25 August 2025 Revised 05 February 2026 Accepted 12 February 2026 Published 20 March 2026 Volume 6 - 2026 Edited by Kapila Seneviratne, University of Kelaniya, Sri Lanka Reviewed by Marina Ramal Snchez, University of Teramo, Italy Ruchika Maurya, Medical University of South Carolina, United States Raz Abdulqadir, The Pennsylvania State University (PSU), United States Updates Copyright 2026 Ryan and Brayden